Sodium Thiosulphate
Also spelled Sodium Hyposulfite or Hypo or Sodium Thiosulfate, Sodium Thiosulphate is an efflorescent and monoclinic crystalline compound that is used for a wide range of applications.

One of the most useful characteristics is its ability to react with dilute acids to produce Sulphur, Sulphur Dioxide and Water; this reaction is sometimes referred to as a 'clock reaction'.

Sodium Thiosulphate should always be stored in tightly sealed containers, away from incompatible materials such as strong acids, Iodine and Mercury. In addition, one should wear appropriate protective clothing while handling it and ensure that store containers storing is kept away from children and animals.

A colorless crystalline compound and also known for its effectiveness and purity and more familiar as the pentahydrate. It is an efflorescent, monoclinic crystalline substance is also called sodium hyposulfite or hypo.

  • Appearance/Form : Colorless crystalline
  • Molecular Formula : Na2S2O3 5H2O
  • Molecular Weight  : 248.19
  • Density               : 1.01 g/mL
  • Solubility             : Soluble in water

  • As a fixative in Photography Industry, both for processing film and photographic paper dissolving silver halides from photographic emulsions.
  • As a reducing agent, water purifying agent and nitrogen exhaust neutralizer.
  • To extract gold from the slurry.
  • As an anti-fungal treatment in Footbaths and for ringworm.
  • As a treatment for patients with end-stage renal disease and in chemotherapy treatments.
  • As a titrant in iodometry in Analytical Chemistry.
  • As an antidote to Cyanide poisoning and counteract the effects of Cyanide Poisoning.
  • As an ingredient in the production of bleach, in pH testing of bleach substances.
  • As an ingredient to De-chlorinate tap water for aquariums and to treat effluent from waste water treatments prior to release into rivers and streams.
  • In the tanning of leather as well as in chemical heating pads and hand-warmers.
  • To lower levels of Chlorine in swimming pools and spas and to remove Iodine stains.
Storage And Handling

Sodium Thiosulphate Storage
  • Store containers containing it in a cool and dry place
  • Prevent exposure of containers containing it into direct sunlight, water and moisture
  • Avoid contact with strong acid, oxidants.
  • Do not store for long time.
  • Avoid Sodium Thiosulphate contact with eyes and skin for it may cause irritation to the eyes, mucous membranes of the upper respiratory tract and allergic skin reactions.
  • Keep containers away from sodium nitrite and metal nitrates.
  • Ingestion of this (especially in large volumes) can irritate the tissues of the mouth, esophagus, and other tissues of the digestive system
  • Avoid breathing dusts.
  • Avoid exposure to high temperatures.
  • Wash thoroughly after handling
Sodium Thiosulphate Manufacturers
Vishnupriya Chemicals, Sodium Thiosulphate manufactures high purity that are virtually free of impurities. The Product is rigorously tested to confirm that they do not contain impurities beyond standard limits.

Sodium Thiosulphate Suppliers
A reputed Sodium Thiosulphate Suppliers of Vishnupriya Chemicals offers them in different sizes at very competitive prices.

Sodium Thiosulphate Traders
A leading Sodium Thiosulphate traders, Vishnupriya Chemicals provides the best quality known for its extensive industrial applications.
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Material Safety Data Sheet

Sodium Thiosulphate (Pentahydrate)


Section 1: Chemical Product and Company Identification


Chemical Name: Thiosulfuric Acid, disodium salt,



CAS#: 10102-17-7

RTECS: WE6660000

TSCA: TSCA 8(b) inventory: No products were found.

CI#: Not available.

Synonym: Ametox, Antichlor; Sodium Hyposulfite,


Chemical Formula: Na2S2O3.5H20


Contact Information:


Vishnupriya Chemicals Pvt. Ltd.


Office No. 7, Meridian apartments

Lake Hills Road, New MLA Quarters

Basheerbagh, Hyderabad 63,  A.P

Tel :  040 - 23225550

Fax : 040 23223177

Email :

Website :


Section 2: Composition and Information on Ingredients






% by Weight

Sodium Thiosulphate (Pentahydrate)




Toxicological Data on Ingredients:  Sodium thiosulfate pentahydrate LD50: Not available. LC50: Not available.


Section 3: Hazards Identification


Potential Acute Health Effects:

Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant), of eye contact



Potential Chronic Health Effects:

Slightly hazardous in case of skin contact (irritant, sensitizer).






Section 4: First Aid Measures


Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.


Skin Contact:

Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.

Cold water may be used.


Serious Skin Contact: Not available.



If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.


Serious Inhalation: Not available.



Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.


Serious Ingestion: Not available.


Section 5: Fire and Explosion Data


Flammability of the Product: Non-flammable.


Auto-Ignition Temperature: Not applicable.


Flash Points: Not applicable.


Flammable Limits: Not applicable.


Products of Combustion: Not available.


Fire Hazards in Presence of Various Substances: Not applicable.


Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.


Fire Fighting Media and Instructions: Not applicable.


Special Remarks on Fire Hazards: When heated to decomposition it emits toxic fumes of sulfur oxides, hydrogen sulfide, and sodium oxide


Special Remarks on Explosion Hazards: An explosion may occur if triturated with nitrates, chlorates, or permanganates.


Section 6: Accidental Release Measures


Small Spill:

Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.


Large Spill:

Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.


Section 7: Handling and Storage



Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If you feel unwell, seek medical attention and show the label when possible. Keep away from incompatibles such as oxidizing agents, acids, alkalis.


Storage: Hygroscopic. Keep container tightly closed. Keep container in a cool, well-ventilated area.


Section 8: Exposure Controls/Personal Protection


Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.


Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.


Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.


Exposure Limits: Not available.


Section 9: Physical and Chemical Properties


Physical state and appearance: Solid.


Odor: Odorless.


Taste: Saline.


Molecular Weight: 248.19 g/mole


Color: Colorless. White.


pH (1% soln/water): pH of a 5% solution: 6.0-8.4


Boiling Point: >100C (212F)


Melting Point: 48C (118.4F)


Critical Temperature: Not available.


Specific Gravity: 1.7 - 1.75(Water = 1)


Vapor Pressure: Not applicable.


Vapor Density: Not available.


Volatility: Not available.


Odor Threshold: Not available.


Water/Oil Dist. Coeff.: Not available.


Ionicity (in Water): Not available.


Dispersion Properties: See solubility in water.



Soluble in cold water, hot water.

Solubility in water:

79 g/100 ml @ 4 deg. C (39 deg. F)

680 g/liter @ 20 deg. C


Section 10: Stability and Reactivity Data


Stability: The product is stable.


Instability Temperature: Not available.


Conditions of Instability: Incompatible materials, moisture


Incompatibility with various substances: Reactive with oxidizing agents, acids, alkalis.


Corrosivity: Non-corrosive in presence of glass.


Special Remarks on Reactivity:

It is a strong reducing and can react with oxidizers.

Reacts with acids to release sulfur dioxide.

Sodium Thiosulfate pentahydrate dissolves in its own water of hydation; it effloresces in warm dry air.

Sodium Thiosulfate pentahydrate loses water at 100 deg. C.

It is incompatible with iodine, acids, lead, mercury, and silver salts (e.g. silver nitrate), halogens.

Hygroscopic; keep container tightly closed. Protect from moisture


Special Remarks on Corrosivity: Not available.


Polymerization: Will not occur..


Section 11: Toxicological Information


Routes of Entry: Inhalation. Ingestion.


Toxicity to Animals:

LD50: Not available.

LC50: Not available.


Chronic Effects on Humans: Not available.


Other Toxic Effects on Humans:

Hazardous in case of ingestion, of inhalation.

Slightly hazardous in case of skin contact (irritant).


Special Remarks on Toxicity to Animals: Not available.


Special Remarks on Chronic Effects on Humans: Not available.


Special Remarks on other Toxic Effects on Humans:

Acute Potenial Health Effects:

Skin: It may cause mild skin irritation.

Eyes: Can cause mechanical eye irritation.

Inhalation: May cause upper respiratory tract and mucous membrane irritation.

Ingestion: Sodium Thiosulfate is an agent with a low order of toxicity. Ingestion of large doses may cause gastrointestinal irritation disturbances with nausea, vomiting, addominal cramping, diarrhea, metabolic acidosis, and hypernatremia. May also affect respiration (cyanosis, respiratory stimulation), cardiovascular(hypotension), behavior (ataxia, convulsions)

Chronic Potential Health Effects:

Skin: Prolonged or repeated skin contact may allergic dermatitis, and irritation.

The toxicological preperties of this substance have not been fully investigated.


Section 12: Ecological Information


Ecotoxicity: Not available.


BOD5 and COD: Not available.


Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.


Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.


Special Remarks on the Products of Biodegradation: Not available.


Section 13: Disposal Considerations


Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.




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